Pharmacological Modulation of Cognitivr Test Solution in Mice of Two Genotypes

Capa

Citar

Texto integral

Acesso aberto Acesso aberto
Acesso é fechado Acesso está concedido
Acesso é fechado Somente assinantes

Resumo

Mice of two strains selected for successful solution of “object permanence” test and for lack of such solution demonstrated the differential reaction to injections of two drugs. The injections of atomoxetine. which blocks the noradrenaline reuptake, and of ‘non-benzodiazepine” anxiolytic afobazol was different. The success of solutions increased in mice selected for this test “non-solution”: and decreased or was inefficient in mice, selected for successful solution of object permanence cognitive test.

Sobre autores

O. Perepelkina

Lomonossov Moscow State University

Email: ingapoletaeva@mail.ru
Rússia, Moscow

I. Poletaeva

Lomonossov Moscow State University

Autor responsável pela correspondência
Email: ingapoletaeva@mail.ru
Rússia, Moscow

Bibliografia

  1. Полетаева И.И., Перепелкина О.В., Зорина З.А. // Биофизика. 2023. Т. 68, № 5, С. 1046–1056.
  2. Galsworthy M.J., Paya-Cano J. L., Liu L., et al. // Behav. Genet. 2005. V. 35, № 5. P. 675-692
  3. Cuevas J., Rodriguez A., Behensky A., et al. // J Pharmacol Exp Ther 2011. V. 339. P. 161–172.
  4. Уянаев А.А., Фисенко В.П. Хитров Т.К. // Бюлл. эксп. Биол. мед. 2003. Т.136. №2. 162–164.
  5. Baria A., Xua S., Pignatelli M. et al. // PNAS. 2020. V. 117. №46. P. 29080–29089
  6. Ptukha M., Fesenko Z., Belskaya A., et al. // Biomolecules 2022, 12, 1484.
  7. Perepelkina O.V., Poletaeva I.I. // Neurol. Int. 2023. V. 15. № 2. P. 649-660;
  8. Chloe S. Chernoff C.S., Hynes T.J., et al. // Psychopharmac. 2024. V. 241. P.767–783.
  9. Ptukha M., Fesenko Z., Belskaya A., et al. // Biomolecules 2022, 12, 1484.
  10. Cain R.E., Wasserman M.C., Waterhouse B.D., McGaughy J.A. // Dev Cogn Neurosci. 2011. V. 1.№ 4. P. 552–559.
  11. Salomons A. R., Arndt S.S., Ohl F. // J. Behav. Brain Sci. 2013. №3. P. 210-216
  12. Калинина Т.С., Шимширт А.А., Волкова А.В., и др. // Эксп. клин. фармак. 2016. Т. 79. № 10. С. 3–7.
  13. Robinson E.D.J. // Psychopharm. 2012. V. 219. P. 303–312.
  14. Robbins T.W. // Br J Pharmacol. 2017. V. 174. № 19. P. 3191–3199

Arquivos suplementares

Arquivos suplementares
Ação
1. JATS XML

Declaração de direitos autorais © Russian Academy of Sciences, 2024