Characteristics of the Cohort of Personnel of the Sublimate Production of the Siberian Chemical Plant Involved in Working with Plutonium-239

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Abstract

239Pu has the property of initiating radiogenic diseases in workers who come into contact with it during their professional activities. To study adverse medical and biological effects and to study in detail the potential consequences of plutonium exposure on the body of personnel at nuclear energy facilities, it is necessary to form a cohort of people involved in working with this isotope. The purpose of the study is to form and characterize a cohort of Siberian Chemical Plant sublimation production employees involved in working with 239Pu in the period 1953–2000. The source of information for forming the cohort was the database of the regional medical and dosimetric register of the population of closed administrative-territorial formation Seversk and the personnel of the Siberian Chemical Plant, containing personal, dosimetric, medical and biological information regarding all current and former employees of the Siberian Chemical Plant (about 65,000 people) since the founding of the enterprise till now. As part of this work, a cohort of sublimation production employees involved in working with 239Pu 9 in 1953–2000 was formed (1,052 people, 577 men and 475 women). The dosimetric, medical and biological characteristics of workers included in the sublimation production cohort are given. The created sublimation production cohort will make it possible to conduct comprehensive retrospective and prospective epidemiological studies to assess the morbidity and mortality of nuclear energy facilities employees, as well as to draw scientifically based conclusions regarding the role of 239Pu in the initiation of the most important socially significant non-infectious diseases (for example, malignant neoplasms, diseases of the circulatory system etc.) and mortality from these diseases. The scientific data obtained as a result of this study will make it possible to determine the main directions for organizing a system for assessing risks to the health of personnel at sites for the decommissioning of nuclear facilities and the formation of a set of measures aimed at improving the health-saving system of nuclear facilities employees and extending their working longevity.

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About the authors

Dmitry E. Kalinkin

Seversk Biophysical Research Center of the Federal Medical-Biological Agency; Siberian State Medical University

Author for correspondence.
Email: kalinkin750@gmail.com
ORCID iD: 0000-0002-6948-6075
Russian Federation, Seversk; Tomsk

Galina V. Gorina

Seversk Biophysical Research Center of the Federal Medical-Biological Agency

Email: gorina.gal@mail.ru
ORCID iD: 0009-0004-7019-6843
Russian Federation, Seversk

Olesya V. Litvinova

Seversk Biophysical Research Center of the Federal Medical-Biological Agency

Email: litvinovaspiridonova@mail.ru
ORCID iD: 0009-0003-5395-4297
Russian Federation, Seversk

Ivan V. Milto

Seversk Biophysical Research Center of the Federal Medical-Biological Agency; Siberian State Medical University

Email: milto_bio@mail.ru
ORCID iD: 0000-0002-9764-4392
Russian Federation, Seversk; Tomsk

Anas R. Takhauov

Seversk Biophysical Research Center of the Federal Medical-Biological Agency

Email: Anas.t@inbox.ru
ORCID iD: 0000-0001-8712-5815
Russian Federation, Seversk

Liliya R. Takhauova

Seversk Biophysical Research Center of the Federal Medical-Biological Agency; Siberian State Medical University

Email: tahauovaa@gmail.com
ORCID iD: 0000-0002-6261-9795
Russian Federation, Seversk; Tomsk

Yulia A. Samoilova

Siberian Federal Scientific Clinical Center of the Federal Medical-Biological Agency

Email: samoilovaua@med.tomsk.ru
ORCID iD: 0009-0000-6407-7945
Russian Federation, Seversk

Alexandr B. Trivozhenko

Siberian Federal Scientific Clinical Center of the Federal Medical-Biological Agency

Email: borisah@yandex.ru
ORCID iD: 0000-0001-6449-9523
Russian Federation, Seversk

Viktor A. Avkhimenko

Siberian Federal Scientific Clinical Center of the Federal Medical-Biological Agency

Email: kb81@med.tomsk.ru
ORCID iD: 0000-0002-2178-601X
Russian Federation, Seversk

Ravil M. Takhauov

Seversk Biophysical Research Center of the Federal Medical-Biological Agency; Siberian State Medical University

Email: niirm2007@yandex.ru
ORCID iD: 0000-0002-1994-957X
Russian Federation, Seversk; Tomsk

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