Synthesis and Biological Activity of 1-Hydroxyethyl- and 1-(4-Hydroxyphenyl)-5-Aryl-4-Aroyl-3-Pyrrolin-2-Ones
- Авторлар: Gein V.L.1, Batov V.A.1, Rubtsov D.F.1, Nosova N.V.1,2, Mokrushin I.G.3, Gein L.F.2, Gagarina A.A.1, Novikova V.V.1, Makhmudov R.R.3,4
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Мекемелер:
- Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
- Perm State Medical University named after Academician E. A. Wagner of the Ministry of Health of the Russian Federation
- Perm State National Research University
- Federal Scientific Center for Medical and Preventive Technologies for Health Risk Management
- Шығарылым: Том 95, № 7-8 (2025)
- Беттер: 245-255
- Бөлім: Articles
- URL: https://transsyst.ru/0044-460X/article/view/692696
- DOI: https://doi.org/10.31857/S0044460X25070029
- EDN: https://elibrary.ru/spkzsv
- ID: 692696
Дәйексөз келтіру
Аннотация
New 1-(2-hydroxyethyl)- and 1-(4-hydroxyphenyl)-5-aryl-4-aroyl-3-hydroxy-3-pyrroline-2-ones were synthesized by the reaction of methyl esters of aroylpyruvic acids, aromatic aldehydes and ethanolamine (p-aminophenol). The antimicrobial and antinociceptive activity of the obtained compounds was studied.
Авторлар туралы
V. Gein
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
Email: geinvl48@mail.ru
Perm, 614990 Russia
V. Batov
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
Email: geinvl48@mail.ru
Perm, 614990 Russia
D. Rubtsov
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
Email: geinvl48@mail.ru
Perm, 614990 Russia
N. Nosova
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation; Perm State Medical University named after Academician E. A. Wagner of the Ministry of Health of the Russian Federation
Email: geinvl48@mail.ru
Perm, 614990 Russia; Perm, 614990 Russia
I. Mokrushin
Perm State National Research University
Email: geinvl48@mail.ru
Perm, 614068 Russia
L. Gein
Perm State Medical University named after Academician E. A. Wagner of the Ministry of Health of the Russian Federation
Email: geinvl48@mail.ru
Perm, 614990 Russia
A. Gagarina
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
Email: geinvl48@mail.ru
Perm, 614990 Russia
V. Novikova
Perm State Pharmaceutical Academy of the Ministry of Health of the Russian Federation
Email: geinvl48@mail.ru
Perm, 614990 Russia
R. Makhmudov
Perm State National Research University; Federal Scientific Center for Medical and Preventive Technologies for Health Risk Management
Хат алмасуға жауапты Автор.
Email: geinvl48@mail.ru
Perm, 614068 Russia; Perm, 614045 Russia
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