The first representatives of phosphonium salts based on the ammonium acylhydrazone scaffold: synthesis and biological activity

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The acid-catalyzed reaction of substituted benzaldehydes with Girard’s reagent T leads to the formation of new water-soluble mixed ammonium-phosphonium salts. The obtained compounds exhibit high antimicrobial and moderate antitumor activities with low hemotoxicity.

作者简介

A. Bogdanov

Kazan (Volga region) Federal University

Email: abogdanov@inbox.ru

S. Bukharov

Kazan National Research Technological University

M. Rozhkova

Kazan National Research Technological University

A. Voloshina

A.E. Arbuzov Institute of Organic and Physical Chemistry, Federal Reseatch Center “Kazan Scientific Center of the Russian Academy of Sciences”

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