SILVER-CONTAINING COLLAGEN-CHITOSAN MATERIALS FOR MEDICAL APPLICATIONS: SYNTHESIS AND STRUCTURE

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Abstract

New collagen-chitosan materials modified by (containing) Ag nanoparticles promising for creating wound coatings are based on a porous hybrid material obtained from collagen and chitosan in powder and gel forms. The paper presents an original process concept of the hybrid biomaterials formation. Powders of collagen and chitosan polymers previously modified with Ag nanoparticles obtained by metal-vapor synthesis were used for synthesis of the materials. Metal containing powder systems with Ag particles were used as precursors for gels preparation after lyophilization of which porous hybrid materials were obtained. Nanocomposites were studied using XPS, PXRD and SEM/EDX methods. A homogeneous distribution of Ag nanoparticles over the collagen-chitosan composite volume was recorded and the composition and electronic states of the metal in the material were studied.

About the authors

P. R Voloshina

Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences

Email: alexandervasilkov@yandex.ru
Moscow, 119334 Russia

A. S Golub

Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences

Email: alexandervasilkov@yandex.ru
Moscow, 119334 Russia

A. Yu Pereyaslavtsev

Dukhov Automatics Research Institute

Email: alexandervasilkov@yandex.ru
Moscow, 115304 Russia

K. M Borisov

Enikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences

Email: alexandervasilkov@yandex.ru
Moscow, 117393 Russia

N. S Melekhina

Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences

Author for correspondence.
Email: alexandervasilkov@yandex.ru
Moscow, 119334 Russia

A. Yu Vasil'kov

Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences

Email: alexandervasilkov@yandex.ru
Moscow, 119334 Russia

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