In vitro Interaction of Titin and Myosin-Binding Protein C

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

The morphological and structural features of coaggregates of two muscle proteins of the sarcomeric cytoskeleton (titin and myosin-binding protein C) were studied using atomic force microscopy, FTIR spectroscopy, fluorimetry using the dye thioflavin T and X-ray diffraction. It was found that, depending on the ionic strength of the solution, coaggregation of these proteins occurs with the formation of structures with different morphologies. The data obtained in vitro expand the understanding of the peculiarities of aggregation of sarcomeric muscle proteins and are important for a better understanding of their interaction in sarcomeres in vivo.

Авторлар туралы

T. Uryupina

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences

Pushchino, Russia

M. Timchenko

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences

Pushchino, Russia

L. Bobyleva

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences

Pushchino, Russia

N. Penkov

Institute of Cell Biophysics, Russian Academy of Sciences

Pushchino, Russia

A. Gabdulkhakov

Institute of Protein Research, Russian Academy of Sciences

Pushchino, Russia

P. Nekrasov

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences

Pushchino, Russia

S. Udalsov

Institute of Physicochemical and Biological Problems of Soil Science

Pushchino, Russia

I. Vikhlyantsev

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences; Pushchino Branch of the Russian Biotechnological University (BIOTECH University)

Pushchino, Russia; Pushchino, Russia

A. Bobylev

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences; Sirius University of Science and Technology

Email: bobylev1982@gmail.com
Pushchino, Russia; Sirius Federal Territory, Russia

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