Russian Journal of GeneticsRussian Journal of GeneticsГенетика0016-67583034-5103The Russian Academy of Sciences66717510.31857/S0016675824100022wgepofОБЗОРНЫЕ И ТЕОРЕТИЧЕСКИЕ СТАТЬИReview ArticleThe Meiotic Drive: Intragenomic Competition and SelectionМейотический драйв: внутригеномные конкуренция и отборZakharovI. A.ЗахаровИ. А.
Russian Federation
iaz34@mail.ruVavilov Institute of General Genetics of the Russian Academy of SciencesИнститут общей генетики им. Н.И. Вавилова Российской академии наук161020246010223026022025Copyright ©; 2024, Russian Academy of SciencesCopyright ©; 2024, Российская академия наук2024Russian Academy of SciencesРоссийская академия наукhttps://transsyst.ru/0016-6758/article/view/667175

The article considers the distribution and mechanisms of the meiotic drive as a phenomenon manifested in unequal transmission of gene alleles and/or homologous chromosomes into gametes during meiosis. The meiotic drive has been studied in the most detail in Drosophila, mice, corn and in ascomycete fungi of the genera Neurospora and Podospora. The consequence of the meiotic drive is a shift in the frequencies of alleles in the gene pool and the maintenance of non-adaptive traits in the population.

В статье рассмотрены распространение, механизмы и эволюционное значение мейотического драйва как явления, проявляющегося у гетерозигот в неравной передаче при мейозе в гаметы аллелей гена и/или гомологичных хромосом. Наиболее подробно мейотический драйв изучен у дрозофил, мышей, кукурузы и у грибов-аскомицетов родов Neurospora и Podospora. Следствием мейотического драйва является сдвиг частот аллелей в генофонде популяции и сохранение в популяции неадаптивных признаков.

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