Russian Journal of GeneticsRussian Journal of GeneticsГенетика0016-67583034-5103The Russian Academy of Sciences66688310.31857/S0016675823020133KYLGLQМОЛЕКУЛЯРНАЯ ГЕНЕТИКАStructure and Diversity of Tc1/mariner Transposons in the Genome of the Jellyfish Aurelia auritaСтруктура и разнообразие ДНК-транспозонов Tc1/mariner в геноме ушастой медузы Aurelia auritaUlupovaYu. N.УлуповаЮ. Н.puzakov@ngs.ruPuzakovaL. V.ПузаковаЛ. В.puzakov@ngs.ruPuzakovM. V.ПузаковМ. В.puzakov@ngs.ruFederal Research Center “Kovalevsky Institute of Biology of the Southern Seas”, Russian Academy of SciencesФедеральный исследовательский центр “Институт биологии южных морей им. А.О. Ковалевского” Российской академии наук0102202359214715626022025Copyright ©; 2023, Ю.Н. Улупова, Л.В. Пузакова, М.В. ПузаковCopyright ©; 2023, Ю.Н. Улупова, Л.В. Пузакова, М.В. Пузаков2023Ю.Н. Улупова, Л.В. Пузакова, М.В. ПузаковЮ.Н. Улупова, Л.В. Пузакова, М.В. Пузаковhttps://transsyst.ru/0016-6758/article/view/666883

Transposable elements, DNA transposons and retrotransposons are DNA sequences capable of movement within the genome. It is assumed that they play one of their key roles in adaptive and evolutionary processes. One of the most studied groups of DNA transposons is the infraclass ITm, and in particular the superfamily Tc1/mariner. In this work, we considered the representation, structure, and evolution of Tc1/mariner DNA transposons in the jellyfish Aurelia aurita. It was found that the predominant proportion of Tc1/mariner elements of the jellyfish is represented by the TLE family. A new subfamily of TLE elements called Aurum has been identified. In addition, two groups of elements VS-aura and VS-beplau were found in the Visitor family, which are probably also separate subfamilies. Analysis of the structure and diversity of Tc1/mariner elements showed that at the moment Tc1/mariner transposons in the jellyfish genome are at the stage of degradation and elimination. Almost all elements are deleted or have structural changes, and, accordingly, do not have potentially functional copies.

Мобильные генетические элементы – ДНК-транспозоны и ретротранспозоны – это последовательности ДНК, способные к перемещениям внутри генома. Предполагается, что они играют одну их ключевых ролей в адаптивных и эволюционных процессах. Одной из наиболее изученных групп ДНК-транспозонов является инфракласс ITm и, в частности, суперсемейство Tc1/mariner. В настоящей работе мы рассмотрели представленность, структуру и эволюцию ДНК-транспозонов Tc1/mariner ушастой медузы Aurelia aurita. Было установлено, что преобладающая доля элементов Tc1/mariner медузы представлена семейством TLE. Выявлено новое подсемейство элементов TLE, названное Aurum. Кроме того, в семействе Visitor обнаружены две группы элементов VS-aura и VS-beplau, которые, вероятно, также являются отдельными подсемействами. Анализ структуры и разнообразия элементов Tc1/mariner показал, что в настоящий момент транспозоны Tc1/mariner в геноме медузы находятся на стадии деградации и элиминации. Практически все элементы делетированы или имеют структурные изменения и соответственно не имеют потенциально функциональных копий.

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